Oct 29, 2019 - et al. Association of different tumor necrosis factor alpha promoter allele frequencies with ankylosing spondylitis in HLA-B27 positive individuals. Arthritis Rheum.Jul 9, 2016 - Feb 20, 2018 - May 29, 2019 - Jump to Treatment / Management - Oct 3, 2017 - The full text of this article is available in PDF format. Keywords : Ankylosing spondylitis, Pathophysiology. Outline, Masquer le plan Management and treatment. Etiology This text focuses on the axial involvement in orpha.net/data/patho/GB/uk-Ankylosing-spondylitis.pdf. 1 Download PDF. Abstract; Full Text; PDF Ankylosing spondylitis (AS) is a chronic inflammatory disease that can cause significant functional complications by affecting the TABLE 2. Role of HLA-B27 in pathogenesis of ankylosing spondylitis