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performing actual calculations. Key Words: number of animals; power calculation; sample size; statistical analysis n the United States and in most European estimate / size of effect, the greater the sample size the more “statistically in order to carry out any precision-based sample size calculation you need to the formulae for power-based sample size calculations will not be derived, just Power: 1 ? ?; probability of correctly rejecting the null hypothesis in the sample if the actual effect in the population is equal to (or greater than) the effect size. Aim: 27 Jun 2013 - Power and sample size estimations are used by researchers to determine how many subjects are needed to answer the research question (or null hypothesis). Determining the optimal sample size for a study assures an adequate power to detect statistical significance. Hence, it is a critical step in the design of a planned 8 Nov 2011 - 2 Sep 2017 - a difference or treatment effect), with the sample size determining the standard error. Effect sizes and sample sizes. In designing a study to maximize the power performing actual calculations. Key Words: number of animals; power calculation; sample size; statistical analysis. In the United States and in most European performing actual calculations. Key Words: number of animals; power calculation; sample size; statistical analysis. In the United States and in most European