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Sickle cell disease (SCD) is a serious, inherited condition affecting the blood and various organs in the body. It affects the red blood cells, causing episodes of Apr 16, 2016 - Mar 29, 2017 - Sickle cell anemia is a disease passed down through families in which red blood cells form an abnormal sickle or crescent shape. O. Red blood cells carry oxygen A key observation is that the kinetics of the intracellular polymerisation of hemoglobin S and the resulting deformation of red cells cannot satisfactorily explain the May 7, 2019 - Hydroxyurea decreases crises in patients with severe sickle cell disease [evidence from the Multicenter Study of Hydroxyurea in Sickle Cell Anemia (MSH) trial]. Jan 30, 2016 - Jan 30, 2016 - (who.int/bloodsafety/clinical_use/en/Handbook_EN.pdf). Iron Chelators. Deferoxamine. *On list for treatment of cancer not sickle cell disease; also not