Abstract Background: Androgen insensitivity syndrome (AIS) or testicular feminization is a partial or complete inability of cell response to androgen. The cause is enzymatic defect in synthesis of testosterone, resulting sexually immature phenotypically female, with primary amenorrhea. Testicular Feminization Syndrome. Written by Himabindhu. Medically Reviewed by The Medindia Medical Review Team on Apr 03, 2015. TESTICULAR FEMINIZATION SYNDROME; TFMAlternative titles ANDROGEN INSENSITIVITY SYNDROME; AIS. Androgen insensitivity syndrome. - Condition that results in the partial or complete inability of thecell to respond to androgens. Androgen insensitivity syndrome, previously termed "testicular feminization syndrome," can be divided into complete and partial forms. In CAIS, patients are characterized as having a 46XY karyotype with female external genitalia, bilateral testes, and absence of the Mullerian structures. If androgen RECs are defective in Testicular feminization syndrome, the wolfian ducts shouldn't differentiate into male internal structures? Complete testicular feminization caused by an amino-terminal truncation of the androgen receptor with downstream initiation. Nawata H., Goto K., Okabe T., Nomura M., Yanase T. (2002) Androgen Insensitivity Syndrome (Testicular Feminization). JK SCIENCE. Testicular Feminization Syndrome. Vaneet Kour, Ajay Abrol*. Abstract. Testicular feminization syndrome or androgen insensitivity syndrome is a rare disorder with an. Testicular feminization syndrome is a rare inherited condition in which the individual who is genetically male with internal testes has the external appearance of a female. The syndrome is a form of intersex and is the most common type of male pseudo hermaphroditism. Testicular Feminization. Karyotype: 46XY. Associated syndromes: Gilbert-Dreyfus, Reifenstein's syndrome, and Rosewater syndrome. Gross: testes may be small or normal in size, and may be located in the abdomen, inguinal canal, or labioscrotal folds. The BBC drama tells the story of one woman's life-changing diagnosis with this rare condition. Testicular Feminization Syndrome? I have a question for Bio 30 homework and it says hypothesize the course of action of this disorder, given what you know Testicular feminization is also known as androgen insensitivity syndrome, and involves the insensitivity of various cells in the body to various