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virus leads to the manifestations of viral disease. Viruses come in two basic types, those that have a genome of DNA and those that have a genome of RNA.Chapter 16 Lecture Notes: The Viruses A. Complete, fully assembled virus particle in the extracellular phase = virion. B. Nucleic acids: Table 16.1. Virus means “poison”. • Viruses have many features more characteristic of complex chemicals (e.g., still infective following. Microbiology & Diseases: Viruses, Prions & Viroids; Ziser Lecture Notes 2014.4. 6. 2. enzymes may dissolve a hole in cell membrane of host. 3. entire virus Notes acid, either DNA or RNA but never both. estimating the size of virus particles was by passing them through collodion membrane filters of graded is a virus classification system that groups viruses into families, depending on their type of genome (DNA, RNA, single-stranded (ss), double-stranded (ds), Viruses replicate or multiply only within living cells. Viruses are obligate intracellular parasites. The term virus was coined by Pasteur, and is from the A. Virus- tiny particle consisting of a nucleic acid core surrounded by a A. Definition: complex viruses that infect bacteria (Fig 23-2d). NOTES.